Caution ought to be worked out when Singulair is given to a nursing mommy because several drugs are excreted in human milk.
No specific information is available on the treatment of overdosage with Singulair.
The efficiency of Singulair for the chronic therapy of asthma in teens and also adults 15 years of age and also older was shown in 2 (U.
In fertility research studies in female rats, montelukast created decreases in fertility and also fecundity indices at an oral dose of 200 mg/kg (approximated direct exposure was around 70 times the AUC for grownups at the maximum recommended daily dental dosage).
Contraceptive pills, Terfenadine, Digoxin, and Warfarin: In medicine interaction research studies, the recommended scientific dosage of montelukast did not have clinically essential impacts on the pharmacokinetics of the complying with drugs: oral contraceptives (norethindrone 1 mg/ethinyl estradiol 35 mcg), warfarin, digoxin, and terfenadine.
Once daily in the evening had a safety and security profile similar to that of placebo, Singulair administered.